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167114-91-2

  • Product Name:Autocamtide 2-related inhibitory peptide
  • Molecular Formula:C64H116 N22 O19
  • Molecular Weight:1822.12
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Product Details

Purity:99%

Good Supplier In China Hot Sale Autocamtide 2-related inhibitory peptide 167114-91-2 Inosine Best Price

  • Molecular Formula:C64H116 N22 O19
  • Molecular Weight:1822.12
  • PSA：746.43000 
  • LogP:8.46970 

Autocamtide 2-related inhibitory peptide (Cas 167114-91-2) Usage

Uses Autocamtide-2-related inhibitory peptide (AIP) is a synthetic peptide that inhibits calmodulin-dependent protein kinase II (CaM kinase II). It is a nonphosphorylatable analog of autocamtide-2. The Autocamtide-2 Related Inhibitory Peptide controls the biological activity of calmodulin-dependent protein kinase II.

167114-91-2 Relevant articles

Critical amino acid residues of AIP, a highly specific inhibitory peptide of calmodulin-dependent protein kinase II

Atsuhiko Ishida, Yasushi Shigeri, Yoshiro Tatsu, Koichi Uegaki, Isamu Kameshita, Sachiko Okuno, Takako Kitani, Noboru Yumoto, Hitoshi Fujisawa

, FEBS Letters, Volume427, Issue1 May 01, 1998 Pages 115-118

The importance of the individual amino acid residues of AIP (KKALRRQEAVDAL), a highly specific inhibitor of calmodulin-dependent protein kinase II (CaMKII), was studied. Replacement of Arg6, Gln7, or Ala9 by other amino acid residues produced a marked increase in the IC50 value.

Side-chain-to-tail thiolactone peptide inhibitors of the staphylococcal quorum-sensing system

R.John Scott a, Lu-Yun Lian c, S.Hanna Muharram b, Alan Cockayne b, Stewart J Wood a, Barrie W Bycroft a, Paul Williams a b, Weng C Chan a

, Bioorganic & Medicinal Chemistry Letters Volume 13, Issue 15, 4 August 2003, Pages 2449-2453

The expression of many staphylococcal virulence factors are regulated by the agr locus via a two-component signal transduction system (TCSTS), which is activated in response to a secreted autoinducer peptide (AIP).

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