1182367-47-0

Quality products make an important contribution to long-term revenue and profitability. Hot Sale Trading Company Sells Rad 140 1182367-47-0 White Powder

1.What is the RAD140 ?

RAD140 is a potent, orally bio-available, and non-steroidal selective androgen receptor modulator (SARM) for the treatment of conditions such as muscle wasting and breast cancer.

2.What is the CAS number for RAD140 ?

The CAS number of RAD140 is 1182367-47-0.

More information of RAD140 1182367-47-0 are:

3.What are another words for RAD140 ?

Synonyms for RAD140 1182367-47-0:2-chloro-4-(((1R,2S)-1-(5-(4-cyanophenyl)-1,3,4-oxadiazol-2-yl)-2-hydroxypropyl)amino)-3-methylbenzonitrile;2-chloro-4-[[(1R,2S)-1-[5-(4-cyanophenyl)-1,3,4-oxadiazol-2-yl]-2-hydroxypropyl]amino]-3-methylbenzonitrile;Testolone;

4.What is the molecular formula of RAD140?

The chemical formula of  RAD140 is C20H16ClN5O2 which containing 20 Carbon atoms,16 Hydrogen atoms,1 Chlorine atoms,5 Nitrogen atoms and 2 Oxygen atoms,and the molecular weight of  RAD140 is 393.832.

5.What is RAD140 (1182367-47-0) used for?

RAD140 (also known as Testolone) is an oral nonsteroidal selective androgen receptor modulator (SARM) that cannot be converted to estrogen by aromatase. It has been demonstrated that RAD140 has high AR affinity and target selectivity, showing marked tissue-selective AR agonist activity comparable to natural androgens in breast cancer cells, while lacking agonist activity in prostate cancer cells.We have recently reported anti-tumor activity of RAD140 in multiple in vivo and in vitro models of AR/ER+ breast cancer as a single agent and in combination with inhibitors of CDK4/6 and mTOR.Pharmacodynamic investigation indicates RAD140 acted as an AR agonist in breast cancer cells while suppressing ER signaling and reduced ESR1 mRNA expression.RAD140 exhibited anti-tumor activity in patient-derived xenograft (PDX) models of AR/ER+ breast cancer, as single agent and in combination with inhibitors of CDK4/6 or mTORRAD140 inhibited ER signaling and ESR1 mRNA level in the HBCx-22 PDX model.

Relevant articles related to RAD140:

6.Buy RAD140 with the best price .

Hebei anda Technology Co., Ltd is a quality supplier of RAD140. Our main goal is customer satisfaction. Contact us to negotiate the best price for your business on RAD140 1182367-47-0.