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5289-74-7

  • Product Name:Hydroxyecdysone
  • Molecular Formula:C27H44O7
  • Molecular Weight:480.642
  • Appearance:white powder
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Product Details

pd_meltingpoint:242-244 °C

Appearance:white powder

Purity:99%

Hydroxyecdysone 5289-74-7 Powder Hot Sale Selling Trading Company

  • Molecular Formula:C27H44O7
  • Molecular Weight:480.642
  • Appearance/Colour:white powder 
  • Vapor Pressure:8.7E-23mmHg at 25°C 
  • Melting Point:242-244 °C 
  • Refractive Index:1.596 
  • Boiling Point:702.1 °C at 760 mmHg 
  • PKA:14.13±0.70(Predicted) 
  • Flash Point:392.4 °C 
  • PSA：138.45000 
  • Density:1.28 g/cm3 
  • LogP:1.85400 

Hydroxyecdysone(Cas 5289-74-7) Usage

Chemical Properties

White or off-white powder

Uses

insect molting hormone

Definition

ChEBI: An ecdysteroid that is ecdysone substituted by a hydroxy group at position 20.

Biochem/physiol Actions

20-Hydroxyecdysone is an ecdysteroid hormone that plays a key role in insect development, cell proliferaton, growth and apoptosis by controlling gene expression involved in molting and metamorphosis. It acts through a heterodimeric receptor comprising the ecdysone receptor and the ultraspiracle proteins (USP).

Purification Methods

Crystallise -ecdyson from water, tetrahydrofuran/pet ether, MeOH and EtOAc after chromatographic purification. It has max (EtOH) at 240nm ( 12,670 M-1cm-1). [Also IR & NMR: Hüppi & Siddall J Am Chem Soc 89 6799 1967, Kametani et al. Tetrahedron Lett 21 4855 1980, Beilstein 8 IV 343.]

InChI:InChI=1/C27H44O7/c1-23(2,32)9-8-22(31)26(5,33)21-7-11-27(34)16-12-18(28)17-13-19(29)20(30)14-24(17,3)15(16)6-10-25(21,27)4/h12,15,17,19-22,29-34H,6-11,13-14H2,1-5H3/t15?,17?,19-,20+,21?,22-,24-,25-,26-,27-/m1/s1

5289-74-7 Relevant articles

A furostanol saponin and phytoecdysteroid from roots of Helleborus orientalis

Akin, Sebahat,Anil, Huseyin

, p. 90 - 92 (2007)

A furostanol saponin mixture and a known...

PHYTOECDYSTEROIDS OF PLANTS OF THE GENUS Silene. ECDYSTERONE 20-O-BENZOATE FROM Silene tatarica

Baltaev, U. A.,Darmograi, V. N.,Abubakirov, N. K.

, p. 706 - 708 (1987)

A new ecdysteroid, which has proved to b...

Ecdysone 20-monooxygenase, a cytochrome P450 enzyme from spinach, Spinacia oleracea

Grebenok, Robert J.,Galbraith, David W.,Benveniste, Irene,Feyereisen, Rene

, p. 927 - 933 (1996)

A microsomal preparation isolated from f...

Mechanism of C-2 hydroxylation during the biosynthesis of 20- hydroxyecdysone in Ajuga hairy roots

Nomura, Keiko,Fujimoto, Yoshinori

, p. 344 - 348 (2000)

Feeding synthetic [2β-2H]- and [2α-2H]-c...

A PHYTOECDYSTEROID, TAXISTERONE, FROM TAXUS CUSPIDATA

Nakano, Kimiko,Nohara, Toshihiro,Tomimatsu, Toshiaki,Nishikawa, Masaru

, p. 2749 - 2751 (1982)

A new phytoecdysteroid, taxisterone, was...

A short way to invert configuration of the 2,3-hydroxy groups in ecdysteroids

Savchenko,Kostyleva,Kachala,Khalilov,Odinokov

, p. 995 - 998 (2013/09/02)

3-epi-2-Dehydro-20-hydroxyecdysone and i...

ECDYSTEROID ANALOGUES HAVING PLANT GROWTH PROMOTING ACTIVITY

-

Page/Page column 25, (2012/05/05)

The present disclosure relates to ecdyst...

Stereoselective catalytic hydrogenation of Δ7-6-ketosteroids in the presence of sodium nitrite

Suksamrarn, Apichart,Tanachatchairatana, Tanud,Sirigarn, Chana

, p. 6033 - 6037 (2007/10/03)

Catalytic hydrogenation with Pd-C as a c...

5289-74-7 Process route

Sileneoside B
84699-93-4

Sileneoside B

20-Hydroxyecdysone
5289-74-7

20-Hydroxyecdysone

ecdysterone 22-O-α-D-galactopyranoside
81655-86-9

ecdysterone 22-O-α-D-galactopyranoside

Conditions
Conditions Yield
In water; at 27 ℃; for 528h; galactosidase;
7 mg
10 mg
Turkesterone
41451-87-0

Turkesterone

20-Hydroxyecdysone
5289-74-7

20-Hydroxyecdysone

Conditions
Conditions Yield
With sodium nitrite; palladium on activated charcoal; In ethanol; water; for 1h; under 760 Torr;
67%

5289-74-7 Upstream products

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    19404-87-6

    20-hydroxyecdysone-2,3,22-triacetate

  • 19974-12-0
    19974-12-0

    22-Dehydro-20-hydroxyecdysone

  • 135024-06-5
    135024-06-5

    (20R,22R)-22-hydroxy-2β,3β,14,20,25-pentakis-(trimethyl-silanyloxy)-5β-cholest-7-en-6-one

  • 54289-60-0
    54289-60-0

    (20R,22R)-2β,3β,14,20,22,25-hexakis-(trimethylsilanyloxy)-5β-cholest-7-en-6-one

5289-74-7 Downstream products

  • 144405-75-4
    144405-75-4

    Poststerone

  • 19536-25-5
    19536-25-5

    20-Hydroxyecdysone-2-acetate

  • 22799-02-6
    22799-02-6

    20-Hydroxyecdysone-22-acetate

  • 22799-03-7
    22799-03-7

    20-hydroxyecdysone 2,3-diacetate

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