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pd_meltingpoint:266-267 ºC
Appearance:white to almost white crystalline powder
Purity:99%
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Levamisole hydrochloride is an anthelmintic. The activity of levamisole is about twice as high as that of abscisicidal, and the toxicity and side effects are lower. Levamisole can cause muscle paralysis of roundworms and then excrete them in the feces. It is mainly used as an anti-worm and anti-hookworm.
levamisole.L-N-[(4-methoxyphenyl)sulfonyl]glutamic acid (salt)
toluene
levamisole hydrochloride
| Conditions | Yield |
|---|---|
|
With sodium hydroxide; In water;
|
94.2% |
Levamisole
levamisole hydrochloride
| Conditions | Yield |
|---|---|
|
Levamisole; With sodium metabisulfite; pyrographite; In isopropyl alcohol; for 0.5h;
With hydrogenchloride; pH=4 - 5; Time;
|
92.1% |
The CAS number of Levamisole hydrochloride is 16595-80-5.
More information of Levamisole hydrochloride 16595-80-5 are:
|
CAS Number |
16595-80-5 |
|
Melting Point |
266-267 ºC |
|
Boiling Point |
344.4 ºC at 760 mmHg |
|
Flash Point |
162.1 ºC |
|
Refractive Index |
-126 ° (C=1, H2O) |
|
HS CODE |
29349990 |
|
PSA |
40.90000 |
|
LogP |
2.32160 |
|
Comments |
Further studies reviewed at the present meeting provided information on the incidence and mechanisms of the haematological effects in humans and dogs. The Committee recognized that while continuous dosing of dogs with 1.25 mg/kg bw/day did not result in haemolytic anaemia, this dose did cause the re-emergence of haemolytic anaemia in a number of dogs previously sensitized with 20 mg/kg bw/day of levamisole. Since there is a very small population of humans who are sensitized to levamisole following therapeutic exposure, the Committee concluded that the use of a safety factor of 200 would be appropriate. On this basis, an ADI of 0-6 μg/kg bw was established. |
|
Meeting |
42 |
|
Previous Years |
1990, TRS 799-JECFA 36/31, FNP 41/3-JECFA 36/65, FAS 27-JECFA 36/75. 0-0.003 (TEMPORARY). MRL (TEMPORARY): EDIBLE TISSUES AND MILK (ALL SPECIES): 0.01. TE. TMRL1990, TRS 799-JECFA 36/31, FNP 41/3-JECFA 36/65, FAS 27-JECFA 36/75. 0-0.003 (TEMPORARY). MRL (TEMPORARY): EDIBLE TISSUES AND MILK (ALL SPECIES): 0.01. TE. TMRL |
Synonyms for Levamisole hydrochloride 16595-80-5:Imidazo[2,1-b]thiazole, 2,3,5, 6-tetrahydro-6-phenyl-, monohydrochloride, (-)-;Decaris;Prestwick_294;Tramisole;2,3,5,6-Tetrahydro-6-phenyl-imidazo[2,1-b]thiazole, (S)-;L(-)-Levamisole;Niratic-PurOn hydrochloride;(7S)-7-phenyl-4-thia-1,6-diazabicyclo[3.3.0]oct-5-ene hydrochloride;Tramisol;Ergamisol (TN);L-Tetramisole hydrochloride;Niratic hydrochloride;L-Narpenol;Imidazo[2, 1-b]thiazole, 2,3,5,6-tetrahydro-6-phenyl-, monohydrochloride, L-(-)-;Ergamisol;
The chemical formula of Levamisole hydrochloride is C11H12N2S.HCl which containing 11 Carbon atoms,13 Hydrogen atoms,2 Nitrogen atoms and 1 Chlorine atoms,and the molecular weight of Levamisole hydrochloride is 240.757.
InChI:InChI=1/C11H12N2S.ClH/c1-2-4-9(5-3-1)10-8-13-6-7-14-11(13)12-10;/h1-5,10H,6-8H2;1H/t10-;/m1./s1
Relevant articles related to Levamisole hydrochloride:
|
Article |
Source |
|
Pesticidal compositions in paste form |
- , (2008/06/13) |
|
Process for isolating levamisole from tetramisole |
- , (2008/06/13) |
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