22374-89-6

  • Product Name:4-phenylbutan-2-amine
  • Molecular Formula:C10H15N
  • Molecular Weight:149.236
  • Appearance:colorless liquid
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Product Details

pd_meltingpoint:-50 °C

Appearance:colorless liquid

Purity:99%

Buy High Quality 4-phenylbutan-2-amine, Offer Good Quality 22374-89-6

  • Molecular Formula:C10H15N
  • Molecular Weight:149.236
  • Appearance/Colour:colorless liquid 
  • Vapor Pressure:0.107mmHg at 25°C 
  • Melting Point:-50 °C 
  • Refractive Index:n20/D 1.514(lit.)  
  • Boiling Point:221.5 °C at 760 mmHg 
  • PKA:pKa 10.0 (Uncertain) 
  • Flash Point:97.8 °C 
  • PSA:26.02000 
  • Density:0.936 g/cm3 
  • LogP:2.66670 

2-Amino-4-phenylbutane(Cas 22374-89-6) Usage

Chemical Properties

clear colorless liquid

Uses

2-Amino-4-phenylbutane is used in the synthesis of N-substituted derivatives of (1-methyl-3- phenylpropyl)amine.

Biological Functions

Amphetamine is an indirectly acting adrenomimetic amine that depends for its action on the release of norepinephrine from noradrenergic nerves. Its pharmacological effects are similar to those of ephedrine; however, its CNS stimulant activity is somewhat greater. Both systolic and diastolic blood pressures are increased by oral dosing with amphetamine. The heart rate is frequently slowed reflexively. Cardiac output may remain unchanged in the low- and moderate-dose range. The therapeutic uses of amphetamine are based on its ability to stimulate the CNS. The D-isomer (dextroamphetamine) is three to four times as potent as the L-isomer in producing CNS effects. It has been used in the treatment of obesity because of its anorexic effect, although tolerance to this effect develops rapidly. It prevents or overcomes fatigue and has been used as a CNS stimulant. Amphetamine is no longer recommended for these uses because of its potential for abuse. Amphetamine is useful in certain cases of narcolepsy or minimal brain dysfunction.

Flammability and Explosibility

Notclassified

Safety Profile

A poison by intraperitoneal and parenteral route. Moderately toxic by ingestion.When heated to decomposition it emits toxic vapors of NOx.

Consumer Uses

ECHA has no public registered data indicating whether or in which chemical products the substance might be used. ECHA has no public registered data on the routes by which this substance is most likely to be released to the environment.

InChI:InChI=1/C10H15N/c1-9(11)7-8-10-5-3-2-4-6-10/h2-6,9H,7-8,11H2,1H3/p+1/t9-/m0/s1

22374-89-6 Relevant articles

Direct reductive amination of ketones with ammonium salt catalysed by Cp*Ir(iii) complexes bearing an amidato ligand

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A series of half-sandwich Ir(iii) comple...

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Half-sandwich iridium complexes bearing ...

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Selective introduction of the deuterium ...

Ambient-Temperature Synthesis of Primary Amines via Reductive Amination of Carbonyl Compounds

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22374-89-6 Process route

4-Phenyl-2-butanone
2550-26-7

4-Phenyl-2-butanone

benzylamine
100-46-9

benzylamine

(RS)-1-methyl-3-phenylpropylamine
22374-89-6,22148-77-2,1199266-89-1

(RS)-1-methyl-3-phenylpropylamine

benzaldehyde
100-52-7

benzaldehyde

Conditions
Conditions Yield
With S-selective ω-transaminase from paracoccus denitrificans transaminase; NAD; aldehyde dehydrogenase; In dimethyl sulfoxide; Reagent/catalyst; Enzymatic reaction;
 
1-phenyl-acetone
103-79-7,136675-26-8

1-phenyl-acetone

(RS)-1-methyl-3-phenylpropylamine
22374-89-6,22148-77-2,1199266-89-1

(RS)-1-methyl-3-phenylpropylamine

N-Methyl-N-phenethylamine
589-08-2

N-Methyl-N-phenethylamine

Conditions
Conditions Yield
With ammonium acetate; magnesium; In methanol; water; at 20 - 25 ℃; Yield given. Yields of byproduct given;
 

22374-89-6 Upstream products

  • 2887-98-1
    2887-98-1

    benzalacetone oxime

  • 2550-26-7
    2550-26-7

    4-Phenyl-2-butanone

  • 540-69-2
    540-69-2

    ammonium formate

  • 1896-62-4
    1896-62-4

    (E)-benzalacetone

22374-89-6 Downstream products

  • 104828-64-0
    104828-64-0

    N,N-dimethyl-4-phenyl-2-butanamine

  • 10528-67-3
    10528-67-3

    4-cyclohexyl-2-butanol

  • 138963-86-7
    138963-86-7

    N-(1-phenylbutan-3-yl)benzamide

  • 433236-68-1
    433236-68-1

    (1-methyl-3-phenyl-propyl)-oxalamic acid ethyl ester

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