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pd_meltingpoint:272.0-275℃
Purity:99%
Quality products make an important contribution to long-term revenue and profitability. For Sale Bromazolam 71368-80-4 99% Powder In Medicine
8-Bromo-1-methyl-6-phenyl-4H-s-triazolo[4,3-a][1,4]benzodiazepine is used to study the antianxiety activity, antidepressant and psychotropics for central nervous system.
acetic acid hydrazide
8-bromo-1-methyl-6-phenyl-4H-benzo[f][1,2,4]triazolo[4,3-a][1,4]diazepine
| Conditions | Yield |
|---|---|
|
7-bromo-5-phenyl-1,3-dihydro-2H-benzo[e][1,4]diazepin-2-one; With sodium hydride; In tetrahydrofuran; at 0 ℃; for 0.333333h;
With di-morpholin-4-yl-phosphinic acid chloride; In tetrahydrofuran; at 0 - 20 ℃; for 2h;
acetic acid hydrazide; In tetrahydrofuran; butan-1-ol; at 20 ℃; for 0.166667h;
|
40% |
acetic acid hydrazide
![7-bromo-5-phenyl-1,3-dihydro-2H-benzo[e][1,4]diazepin-2-one](/upload/2023/8/9403ca40-129e-480f-aaf4-c08a7e82760b.png)
7-bromo-5-phenyl-1,3-dihydro-2H-benzo[e][1,4]diazepin-2-one
8-bromo-1-methyl-6-phenyl-4H-benzo[f][1,2,4]triazolo[4,3-a][1,4]diazepine
| Conditions | Yield |
|---|---|
|
7-bromo-5-phenyl-1,3-dihydro-2H-benzo[e][1,4]diazepin-2-one; With sodium hydride; In tetrahydrofuran; at 0 ℃; for 0.333333h;
With di-morpholin-4-yl-phosphinic acid chloride; In tetrahydrofuran; at 0 - 20 ℃; for 2h;
acetic acid hydrazide; In tetrahydrofuran; butan-1-ol; at 20 ℃; for 5.16667h; Heating / reflux;
|
40% |
The CAS number of 8-Bromo-1-methyl-6-phenyl-4H-[1,2,4]triazolo[4,3-a][1,4]benzodiazepine is 71368-80-4.
More information of 8-Bromo-1-methyl-6-phenyl-4H-[1,2,4]triazolo[4,3-a][1,4]benzodiazepine 71368-80-4 are:
|
CAS Number |
71368-80-4 |
|
Density |
1.54±0.1 g/cm3 (20 oC 760 Torr) |
|
Melting Point |
272.0-275℃ |
|
Boiling Point |
519.8±60.0 °C(Predicted) |
|
PSA |
43.07000 |
|
LogP |
3.12480 |
|
Pka |
2.37±0.40(Predicted) |
Synonyms for 8-Bromo-1-methyl-6-phenyl-4H-[1,2,4]triazolo[4,3-a][1,4]benzodiazepine 71368-80-4:8-bromo-1-methyl-6-phenyl-4H-s-triazolo[4,3-a][1,4]benzodiazepine;
The chemical formula of 8-Bromo-1-methyl-6-phenyl-4H-[1,2,4]triazolo[4,3-a][1,4]benzodiazepine is C17H13BrN4 which containing 17 Carbon atoms,13 Hydrogen atoms,1 Bromine atoms and 4 Nitrogen atoms,and the molecular weight of 8-Bromo-1-methyl-6-phenyl-4H-[1,2,4]triazolo[4,3-a][1,4]benzodiazepine is 353.221.
Bromazolam is classified as a novel benzodiazepine which was first synthesised in 1976, but was never marketed. It has subsequently been sold as a designer drug, first being definitively identified by the EMCDDA in Sweden in 2016. It is the bromo instead of chloro analogue of alprazolam, and has similar sedative and anxiolytic effects. Bromazolam is structurally similar to traditional benzodiazepines, including alprazolam (replacing the chlorine with a bromine) and bromazepam (addition of triazole ring). Alprazolam and bromazepam are Schedule IV substances in the United States; bromazolam is not explicitly scheduled.
Relevant articles related to 8-Bromo-1-methyl-6-phenyl-4H-[1,2,4]triazolo[4,3-a][1,4]benzodiazepine:
|
Article |
Source |
|
ANXIOLYTIC AGENTS WITH REDUCED SEDATIVE AND ATAXIC EFFECTS |
- Page/Page column 38-39, (2010/02/07) |
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