Your Location：Home >Products >Pharmaceutical >374675-21-5
Purity:99%
|
Description |
Kisspeptin is a protein present in the hypothalamus (a part of the brain that controls the release of several important hormones in the body). It plays a major role in the control of reproductive hormones in both men and women. Specifically, kisspeptin regulates the release of 'gonadotrophin releasing hormone' (GnRH) from the hypothalamus. |
|
Uses |
As expected, intravenous kisspeptin significantly increased circulating kisspeptin levels (mean difference = 2705 pmol/L [95% CI, 2560-2851 pmol/L]; P < . 001), reaching steady state from 30 to 75 minutes of the kisspeptin infusion. |
Kisspeptin was first discovered in 1996 as a metastasis inhibitor in melanoma cell lines [1]. Kisspeptin is actually a family of peptides derived from the KISS1/kiss1 gene with structural similarity, forming from differential proteolysis of a common precursor, prepro-kisspeptin. Kisspeptin peptides are classified as an RF amide peptide family i.e., neuroactive peptides with characteristic Arg-Phe-NH2 motif...
We, and others, have used a polyclonal rabbit antibody generated by Caraty et al. (AC 566) to detect kisspeptin in the mouse (11, 20, 41) and sheep (16, 25, 27) brain. This polyclonal antibody was raised against the ten amino acid C-terminal of murine kisspeptin (residues 43–52), which are required for activation of GPR54...
CAS：119356-77-3
CAS：868844-74-0
CAS：360-70-3
CAS：106505-90-2
