62-44-2

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1.What is the Phenacetin ?

Acetophenetidin is a fine, white, crystalline powder or solid. Odorless with a slightly bitter taste

ChEBI: Phenacetin is a member of the class of acetamides that is acetamide in which one of the hydrogens attached to the nitrogen is substituted by a 4-ethoxyphenyl group. It has a role as a non-narcotic analgesic, a peripheral nervous system drug and a cyclooxygenase 3 inhibitor. It is a member of acetamides and an aromatic ether. It is functionally related to a N-phenylacetamide, a 4-ethoxyaniline and a paracetamol.

Phenacetin, a painkiller, was the world’s first synthetic pharmaceutical drug. It was one of the first painkillers that was not derived from opium while at the same time being absent of antiinflammatory qualities. Phenacetinwas developed in 1878 by an American chemist, Harmon Northrop Morse. It was introduced into the pharmaceutical market in 1887. However, it was withdrawn in 1983 in the United States due to unacceptable levels of interstitial nephritis in patients and potential risks of tumorigenicity. Like in the United States, most Western countries did not ban phenacetin from marketing until 1983. Phenacetin is a component of APC (aspirin-phenacetin-caffeine).

2.What is the CAS number for Phenacetin ?

The CAS number of Phenacetin is 62-44-2.

3.What are another words for Phenacetin ?

Synonyms for Phenacetin 62-44-2:p-Acetophenetidide(8CI);4-(Acetylamino)phenetole;4-Ethoxy-1-acetylaminobenzene;4-Ethoxyacetanilide;4'-Ethoxyacetanilide;Aceto-4-phenetidine;Acetophenetidin;Acetophenetidine;Acetophenetin;Acetphenetidin;Fenidina;Fenina;Kalmin;N-(4-Ethoxyphenyl)acetamide;N-Acetyl-4-ethoxyaniline;N-Acetyl-p-ethoxyaniline;N-Acetyl-p-phenetidine;NSC 7651;Pertonal;Phenacetin;Phenacetine;Phenazetin;Phenedina;Phenidin;Phenin;p-Ethoxyacetanilide;

4.What is Phenacetin (62-44-2) used for?

Phenacetin was used as an analgesic and fever-reducing drug in both human and veterinary medicine for many years until it was implicated in kidney disease (nephropathy) due to abuse of analgesics and was withdrawn from the market. Phenacetin also was previously used as a stabilizer for hydrogen peroxide in hair-bleaching preparations.

InChI:InChI=1/C10H13NO2/c1-3-13-10-6-4-9(5-7-10)11-8(2)12/h4-7H,3H2,1-2H3,(H,11,12)

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